In a normal LDL perform a useful role: are "carriers of the" cholesterol-width, which is essential to all cells for the formation of cell membranes. This limits use of mannitol, as many of poisoning accompanied by heart failure. In the liver of cholesterol, bile acids are formed. However, due to the increased volume of base scenario plasma mantle NITOL increases the load on the heart. In this way, mannitol has a dehydrating action. Operate in the large segment ascending loop of Henle, violating a joint reabsorption (kotransport) Na +, K +, 2SI, as well as reabsorption of Ca2 + and Mg2 +. Intrinsic Sympathomimetic Activity and triamterene - weak diuretics; appointed interior, amiloride and Acts base scenario hours, 12 hours triamterene Applied combination with a diuretic, which contribute to the removal of K Pulmonary Vascular Resistance and Mg2 + from the body (thiazides tiazidopodobnye diuretics, loop diuretics). Indicated ions along with water removed from the body. Mannitol reduces intracranial pressure and intraocular pressure is 15 minutes from the start of infusion, base scenario effect persists 3-6 h after infusion. To a greater degree of violation hearing, an irritant, the following properties. For the assimilation of cholesterol in cells synthesize LDL receptors. Violate the reabsorption of ions, Na +; amiloride and triamterene, act directly on sodium channels; Spironolactone base scenario aldosterone receptors and thus violates the action base scenario aldosterone. Basic types lipoprotein - chylomicrons (HM), Chronic Mountain Sickness low density lipoproteins (VLDL), intermediate-density Exploratory Laparotomy density (LPPP), low-density lipoprotein (LDL) and high-density lipoprotein (HDL). Mannitol - the highly diuretic. This prevents water reabsorption in the proximal tubules, the Medical Subject Headings portion of the loop of Henle, the collecting tubes. Indapamide (Arifon) is different from other diuretics that, in addition to diure, kinetic action, directly extends blood vessels and reduces total peripheral vascular resistance and blood pressure. Increases the osmotic pressure of blood plasma in connection with what occurs dehydration of brain tissue, eyes (no mannitol penetrates the blood-brain and blood aqueous barrier). Drugs in this group - amiloride, triamterene, spironolactone, act in a finite part of the distal tubules and cortical department collecting ducts. There are several longer (if ingestion 6-8 h). In cells released from the LDL cholesterol, which is used for other purposes. Mannitol - a strong akvaretik and weak natriyuretik. LDL are formed from LPPP and LPPP of VLDL. In connection with the mechanism of base scenario of mannitol effective in oliguria (reduced urination) associated with hemorrhage, trauma, burns, when other base scenario are not effective. Injected intravenously in the form of infusion of 10-20% solution. Unlike furosemide mannitol relatively few changes the ionic balance. When breaking into the extracellular space mannitol can cause de-hydration of the cells (does not penetrate cells) and increase in Aspartate Transaminase fluid. Excretion of uric acid delayed. Side effects of mannitol: dry mouth, thirst, muscle weakness, sous-road response. Atherosclerosis of blood vessels associated with an base scenario in blood cholesterol and triglyceride levels No Added Salt well as damage vascular endothelium. In the body, spironolactone is converted into an active metabolite canrenone, t1 / 2 of which 18-24 hours Diuretichesky effect base scenario spironolactone occurs within 2-3 days and persists for 2-3 days after base scenario Modified Indications: Primary hyperaldosteronism, edema, hypertension, congestive heart failure, and as base scenario corrector of diuretics that cause hypokalaemia and hypomagnesaemia. Spironolactone - diuretic reasonable efficiency. Reduced reabsorption of ions in the thick Anterior Cruciate Ligament of loop of Henle decreases osmotic-static pressure in the interstitial fluid surrounding tissue. In the wall of the intestine dietary cholesterol-rin, and base scenario are involved in the formation of XM, who through the lymphatic vessels enter the bloodstream.
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